Thursday, July 4, 2013

FTC approves settlement with HTC over logging software

FTC approves settlement with HTC over logging software

In late February the FTC and HTC came to a tentative settlement over the manufacturer's poorly secured software, which included HTC Loggers. The commission voted three to none, with one commissioner recused, to require the company to patch the vulnerabilities and develop a security program that would undergo an independent assessment every other year for the next two decades. The American arm of HTC will also be watched closely regarding its security and consumer privacy claims. Any statements that are found to be false or misleading could lead to fines of up to $16,000 per violation. With the public comment period closed, the FTC has cleared the last hurdle to enforcing the settlement. Let's just hope others are taking heed, last thing we need is second round of electronic privacy scandals. Oh, wait...

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Source: http://www.engadget.com/2013/07/02/ftc-approves-settlement-with-htc/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Wednesday, July 3, 2013

Microsoft's Xbox One coming to Japan in 2014

Microsofts Xbox One coming to Japan in 2014

It's never nice to be told you're a second class citizen, which is probably why Microsoft was reticent to mention when the Xbox One would launch in Japan. When 4Gamer cornered Japanese VP Yasuyuki Higuchi for answers, he conceded that the country was "tier two," and that the hardware wouldn't arrive there until 2014. On the upside, he did promise that the tier two countries wouldn't be waiting long after the North American release, but that's hardly going to sate early adopters with an eye on the local hero.

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Via: Games Industry

Source: 4Gamer (Translated), DualShockers

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/7_5T-J9scn8/

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Tuesday, July 2, 2013

The ribosome: New target for antiprion medicines

July 2, 2013 ? New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery of the cell. The results were recently published in the Journal of Biological Chemistry.

Prion diseases are fatal neurodegenerative diseases caused by misfolding of prion proteins. Examples of prion diseases are scrapie in sheep, mad cow disease and Creutzfeldt-Jakob disease in human.

What triggers misfolding of the prion proteins to the amyloid disease form is an open question. The inadequate knowledge in the field about the factors involved in prion formation makes the discovery of effective medicines for prion diseases rather challenging.

"We have now shown that the protein folding activity of the ribosome (PFAR) is most likely involved in prion propagation and thus, can be a specific target for antiprion medicines. If we understand the mechanism fully, we will be able to find ways to stop that too.," says Suparna Sanyal, senior lecturer at the Department of Cell and Molecular Biology, Uppsala University .

The ribosome is the protein synthesis machinery of the cell. The mechanism of protein synthesis by the ribosome is well characterized, while PFAR is a rather recent discovery. PFAR is a ribosomal RNA dependent function of the large subunit of the ribosome irrespective of its source. The PFAR center closely overlaps the peptidyl transferase center although the nucleobases responsible for these two functions are not all common.

"Our results show that two prion inhibitors 6-aminophenanthridine and guanabenz acetate implement antiprion activity by binding to ribosomal RNA and inhibiting PFAR. Thus, the ribosome and more specifically PFAR is the new target for antiprion medicines. Furthermore, we have developed an in vitro PFAR assay, which can be used as a platform for screening prion inhibitors in a high-throughput fashion. This assay is much more time and cost-effective than standard prion assays," says Suparna Sanyal.

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The above story is reprinted from materials provided by Uppsala Universitet, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Y. Pang, S. Kurella, C. Voisset, D. Samanta, D. Banerjee, A. Schabe, C. Das Gupta, H. Galons, M. Blondel, S. Sanyal. The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition. Journal of Biological Chemistry, 2013; 288 (26): 19081 DOI: 10.1074/jbc.M113.466748

Note: If no author is given, the source is cited instead.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/Rj_jDfOp4cM/130702100120.htm

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Colin Hanks Welcomes Daughter Charlotte

"Ms. Charlotte Bryant Hanks has decided to join us," the actor, 35, tells PEOPLE exclusively. "She's as happy and healthy as we are overjoyed and tired."

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/BwRNeNgLdao/

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ATD: Microsoft Xbox head Don Mattrick leaving for unknown role (updated)

The president of Microsoft's Interactive Entertainment Business, Don Mattrick, is leaving the company according to a report at AllThingsD. His division oversees the Xbox gaming properties as well as the company's peripheral gaming initiatives. He's most recently known as the man who introduced the world to the Xbox One, as he took the stage on Microsoft's campus this past May to introduce the controller, next-gen Kinect sensor, and new console. He's been with the IEB department since 2010. He's gotten in trouble with consumers lately, after he gave dismissive answers about the Xbox One's always online policy and $499 price point. He's also the man who wrote Microsoft's public DRM reversal letter.

Furthermore, ATD says Mattrick could be headed to social gaming giant Zynga; the Bay Area-based company declined a comment to our sister site Joystiq. It's unclear who would step in to Mattrick's spot if he is indeed leaving. We've yet to hear back from Microsoft, though we'll update this post when we hear more.

Update: It's offical. He's the new CEO of Zynga, and you can read all about it right here.

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Source: AllThingsD

Source: http://www.engadget.com/2013/07/01/don-mattrick-leaving-microsoft/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Law requires Chinese to visit their aging parents

BEIJING (AP) ? Mothers and fathers aren't the only ones urging adult children to visit their parents. China's lawbooks are now issuing the same imperative.

New wording in the law requiring people to visit or keep in touch with their elderly parents or risk being sued came into force Monday, as China faces increasing difficulty in caring for its aging population.

The amended law does little to change the status quo, however, because elderly parents in China already have been suing their adult children for emotional support and the new wording does not specify how often people must visit or clarify penalties for those who do not.

It is primarily aimed at raising awareness of the issue, said one of the drafters, Xiao Jinming, a law professor at Shandong University. "It is mainly to stress the right of elderly people to ask for emotional support ... we want to emphasize there is such a need," he said.

Cleaning lady Wang Yi, 57, who lives alone in Shanghai, said the new law is "better than nothing." Her two sons work several hundred kilometers (miles) away in southern Guangdong province and she sees them only at an annual family reunion.

"It is too little, for sure, I think twice a year would be good," she said. "We Chinese people raise children to take care of us when we are old."

China's legislature amended the law in December following frequent reports of elderly parents neglected by their children. It says offspring of parents older than 60 should see that their daily, financial and spiritual needs are met.

Although respect for the elderly is deeply engrained in Chinese society, three decades of market reforms have accelerated the breakup of China's traditional extended family, and there are few affordable alternatives, such as retirement homes.

Xiao said even before the Law of Protection of Rights and Interests of the Aged was amended, there were several cases of elderly parents suing their children for emotional support. Court officials generally settle such cases by working out an arrangement for sons or daughters to agree to visit more frequently. Typically, no money is involved.

The number of people aged 60 and above in China is expected to jump from the current 185 million to 487 million, or 35 percent of the population, by 2053, according to figures from the China National Committee On Aging. The expanding ratio is due both an increase in life expectancy ? from 41 to 73 over five decades ? and by family planning policies that limit most urban families to a single child.

Rapid aging poses serious threats to the country's social and economic stability, as the burden of supporting the growing number of elderly passes to a proportionately shrinking working population and the social safety net remains weak.

Zhang Ye, a 36-year-old university lecturer from eastern Jiangsu Province, said the amended law was "unreasonable" and put too much pressure on people who migrate away from home in search of work or independence.

"For young people who are abroad or work really far away from their parents, it is just too hard and too expensive to visit their parents," she said. "I often go to visit my parents and call them ... (but) if a young person doesn't want to, I doubt such a law will work."

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AP researchers Flora Ji in Beijing and Fu Ting in Shanghai contributed to this report.

Source: http://news.yahoo.com/law-requires-chinese-visit-aging-parents-063254370.html

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Monday, July 1, 2013

Florida Soccer Expo . September 14-15 . 2013

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PRLog (Press Release) - Jun. 30, 2013 - Miami FL. July 1st, 2013

Soccer Expo in Florida brings soccer fans and families together for a weekend of celebration and excitement

Miami, FL. The organizers of Florida Soccer Expo announced the first event of its kind in Florida bringing together over 8,000 fans at the Sun Life Stadium on September 14th & 15th, 2013. This celebration of ?the beautiful game? will host the soccer community including soccer clubs, associations, tournament organizers, coaches, trainers, referees, soccer families and players from all over the world.

The event is divided in three sections, hosting a trade show, an indoor soccer tournament and interactive areas where the soccer public could participate in numerous soccer-related activities organized by Florida Soccer Expo partners, sponsors and other exhibitors. This highly expected show will include coaching clinics, referee seminars and nutritional & health

Several key soccer associations have been invited and are joining the efforts as Institutional Partners and will contribute with the promotion and success of this event, these include:

? ? ? ? ? Concacaf

? ? ? ? ? AYSO. American Youth Soccer Organization

? ? ? ? ? WPSL. Women Premier Soccer League

? ? ? ? ? Miami Dade Soccer League

? ? ? ? ? Miami Dade Sports Commission

? ? ? ? ? Florida State Referees

? ? ? ? ? Florida State Soccer Association

? ? ? ? ? SunLife Stadium. Miami Dolphins

The expo includes six (6) indoor soccer fields. For those interested in soccer shopping, the event features over 80 exhibitor booths available at the event, including a wide variety of soccer and sports-related products, gear and equipment, food and drinks sampling, and other consumer goods and services. Exhibitors interesting in this event should contact the organization via email at exhibitors@floridasoccerexpo.com, or send a message in our website at www.floridasoccerexpo.com

Source: http://www.prlog.org/12166455-florida-soccer-expo-september-14-15-2013.html

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